3rd Century Christian theologian Origen commenting on Romans 16:1-2 notes that the Myrrhbearing women were not the only females to have served the Church. Women continued serving in recognized offices in the Church throughout the early centuries of Christianity.
“’I commend to you our sister Phoebe, a deacon of the church at Cenchreae, so that you may receive her in the Lord as is fitting for the saints, and help her in whatever she may require from you, for she has helped many and myself as well.’ [Romans 16:1-2]
This passage teaches us, with apostolic authority, that women were appointed to the ministry of the church. Paul describes Phoebe, who held office in the church of Cenchreae, with great praise and commendation. He lists her outstanding deeds and says, she has helped many, ready whenever they were in difficulty, and myself as well, in my troubles and my apostolic labors, with full devotion.
I would compare her work to that of Lot; because he always offered hospitality, he merited to receive angels as guests. Similarly Abraham, who always went out to meet strangers, merited that the Lord and his angels would stop and rest in his tent. In the same way, Phoebe, since she offered and provided assistance to everyone, merited to become a benefactor of the Apostle. This passage provides two lessons: women served as ministers in the church and those appointed to the ministry of the church should be benefactors to many and through their good services merit the praise of the apostles. The passage also encourages Christians to honor those who commit themselves to good works in the church; whether they serve spiritual or fleshly needs, they should be held in honor.” (J. Patout Burns Jr., Romans: Interpreted by Early Christian Commentators, Kindle Loc. 7510-18)